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CHRM3 Antibody (YA3867)(PBS only)

(Synonyms: HM3; PBS; EGBRS; m3AChR)

CHRM3 Antibody (YA3867) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CHRM3.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rabbit

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • CHRM3 Antibody (YA3867)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:200-1:400 1:25-1:50 1:200-1:400

Product Details

Description

CHRM3 Antibody (YA3867) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CHRM3.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rabbit
  • Observed Molecular Weight
    Observed band size: 66 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 66 kDa
Immunogen

Purified fusion protein with human CHRM3 aa 286-461.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CHRM3 is a The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover

  • Subcellular Localization

    Cell membrane; Multi-pass membrane protein; Postsynaptic cell membrane; Multi-pass membrane protein; Basolateral cell membrane; Multi-pass membrane protein; Endoplasmic reticulum membrane; Multi-pass membrane protein

  • Subunit

    Homodimer; the dimers can form tetramers (PubMed:23521066). Interacts with NALCN (By similarity). Interacts with TMEM147 (PubMed:21056967)

  • SwissProt ID

    P20309

  • Gene ID
    1131 [NCBI]
  • Synonyms

    HM3; PBS; EGBRS; m3AChR

CHRM3 Antibody (YA3867)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • CHRM3 Antibody (YA3867)(PBS only) Product Image