CHRNA1 Antibody
(Synonyms: ACHRA, CHNRA, CHRNA1, Acetylcholine receptor subunit alpha)CHRNA1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CHRNA1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
CHRNA1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CHRNA1.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 54 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 54 kDa
Synthetic peptide corresponding to the center region of human CHRNA1.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CHRNA1 is upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane
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Subcellular Localization
Postsynaptic cell membrane; Cell membrane
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Expression
Tissue_Specificity: Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus. -
Isoforms & Post-Translational Modification
CHRNA1 has 2 isoforms, P02708-2: amino acid length is 457, molecular weight is 51839 Da (predicted); P02708-1: amino acid length is 482, molecular weight is 54546 Da (predicted).
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Subunit
One of the alpha chains that assemble within the acetylcholine receptor, a pentamer of two alpha chains, a beta, a delta, and a gamma (in immature muscle) or epsilon (in mature muscle) chains.
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SwissProt ID
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Synonyms
ACHRA, CHNRA, CHRNA1, Acetylcholine receptor subunit alpha
Documentation
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