Calponin-1 Antibody (YA6377)

Cat. No.: HY-P86685: Data Sheet User Guide for Antibodies
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Calponin-1 Antibody (YA6377) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Calponin-1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Calponin-1 Antibody (YA6377) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Calponin-1.

Host

Rabbit

Clonality

Monoclonal

Molecular Weight

Predicted band size: 33 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P51911

Gene ID

1264 [NCBI]

Immunogen

A synthesized peptide derived from human Calponin 1 aa 250-297

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000-10000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-500
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-500

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity)

Expression：
Tissue_specificity:Smooth muscle, and tissues containing a large amount of smooth muscle.

Isoforms & Post-Translational Modification：P51911 has 2 isomers: P51911-1: 33170 Da (predicted); P51911-2: 31055 Da (predicted).

Subunit：Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1

Synonyms

CNN1_HUMAN; Calponin-1; Basic calponin; Calponin H1, smooth muscle; calponin 1; SMCC; Sm-Calp; HEL-S-14;

Documentation

User Guide for Antibodies (1077 KB)