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Cat. No.: HY-P86685

Calponin-1 Antibody (YA6377)

Name: Calponin-1 Antibody (YA6377)
Brand: MedChemExpress
SKU: HY-P86685
Availability: PreOrder

(Synonyms: CNN1_HUMAN; Calponin-1; Basic calponin; Calponin H1, smooth muscle; calponin 1; SMCC; Sm-Calp; HEL-S-14; )

Calponin-1 Antibody (YA6377) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Calponin-1.

For research use only. We do not sell to patients.

Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	IHC-F IHC-F: Immunohistochemistry-Frozen
Dilution Ratio	1:2000-10000	1:100-500	1:100-500	1:100-500

Description

Calponin-1 Antibody (YA6377) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Calponin-1.

Immunogen

A synthesized peptide derived from human Calponin 1 aa 250-297

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

Calponin-1 is a Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity
Expression

Tissue_specificity:Smooth muscle, and tissues containing a large amount of smooth muscle.
Isoforms & Post-Translational Modification

P51911 has 2 isomers: P51911-1: 33170 Da (predicted); P51911-2: 31055 Da (predicted).
Subunit

Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1
SwissProt ID

P51911
Gene ID

1264 [NCBI]
Synonyms

CNN1_HUMAN; Calponin-1; Basic calponin; Calponin H1, smooth muscle; calponin 1; SMCC; Sm-Calp; HEL-S-14;