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CNOT2 Antibody (YA8379)

(Synonyms: CDC36; HSPC131; NOT2; NOT2H)

CNOT2 Antibody (YA8379) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CNOT2.

For research use only. We do not sell to patients.

Host:
Mouse
Isotype:
IgG2a
Application:
WB, IHC-P
Reactivity :
Human, Mouse, Rat

Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Conjugation:
Non-conjugated

Tamaño

Precio

Stock

Cantidad

Sample (0.1mg)

In-stock

(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications
Product Details
Product Properties
- Appearance
- Formulation
- Envío
Background
Documentación
Help & FAQs
Bioz

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio	1:1000-2000	1:150-500

Product Details

Descripciòn

CNOT2 Antibody (YA8379) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CNOT2.

Host Mouse
Clonality Monoclonal
Species Reactivity
Human, Mouse, Rat
Calculated Molecular Weight Predicted band size: 59.6 kDa

Immunogen

Full length human recombinant protein of human CNOT2 produced in E.coli.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2a

Product Properties

Appearance

Solution
Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Envío

Shipping with blue ice.

Background

Function

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of embryonic stem (ES) cell identity
Subcellular Localization

Cytoplasm,Nucleus
Expression

Tissue_Specificity: Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes
Isoforms & Post-Translational Modification

Q9NZN8 has 5 isomers: Q9NZN8-1: 59738 Da (predicted); Q9NZN8-2: 40818 Da (predicted); Q9NZN8-3: 22254 Da (predicted); Q9NZN8-4: 51537 Da (predicted); Q9NZN8-5: 54306 Da (predicted).
Subunit

Component of the CCR4-NOT complex; distinct complexes seem to exist that differ in the participation of probably mutually exclusive catalytic subunits
SwissProt ID

Q9NZN8
Synonyms

CDC36; HSPC131; NOT2; NOT2H