CNTN4/AXCAM Antibody (YA7161) (PBS only)
(Synonyms: Contactin-4, Brain-derived immunoglobulin superfamily protein 2, BIG-2, CNTN4)CNTN4/AXCAM Antibody (YA7161)(PBS only) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CNTN4/AXCAM.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in PBS.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:1000-2000 |
Product Details
CNTN4/AXCAM Antibody (YA7161)(PBS only) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CNTN4/AXCAM.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 150kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 113kDa
A synthesized peptide derived from human Contactin 4
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CNTN4/AXCAM is a Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis
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Subcellular Localization
Cell membrane; Secreted
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Expression
Tissue_Specificity: Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex.
Induction: By retinoic acid, suggesting that it may act in response to differentiating agents. -
Isoforms & Post-Translational Modification
CNTN4/AXCAM has 4 isoforms, Q8IWV2-1: amino acid length is 1026, molecular weight is 113454 Da (predicted); Q8IWV2-2: amino acid length is 282, molecular weight is 31066 Da (predicted); Q8IWV2-3: amino acid length is 697, molecular weight is 76527 Da (predicted); Q8IWV2-4: amino acid length is 698, molecular weight is 76655 Da (predicted).
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Subunit
Interacts with PTPRG
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SwissProt ID
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Synonyms
Contactin-4, Brain-derived immunoglobulin superfamily protein 2, BIG-2, CNTN4