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Cat. No.: HY-P87474

CNTN4/AXCAM Antibody (YA7161)

CNTN4/AXCAM Antibody (YA7161) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CNTN4/AXCAM.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Stock

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot
Dilution Ratio	1:1000-2000

Description

CNTN4/AXCAM Antibody (YA7161) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CNTN4/AXCAM.

Host Rabbit
Clonality Recombinant
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 150kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 113kDa

Immunogen

A synthesized peptide derived from human Contactin 4

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

CNTN4/AXCAM is a Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis
Subcellular Localization

Cell membrane,Secreted
Expression

Tissue_Specificity: Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex
Induction: By retinoic acid, suggesting that it may act in response to differentiating agents
Isoforms & Post-Translational Modification

Q8IWV2 has four isomers: Q8IWV2-1: 113454 Da (predicted); Q8IWV2-2: 31066 Da (predicted); Q8IWV2-3: 76527 Da (predicted); Q8IWV2-4: 76655 Da (predicted).
Subunit

Interacts with PTPRG
SwissProt ID

Q8IWV2