COSMC Antibody
(Synonyms: COSMC, HSPC067, MSTP143, UNQ273/PRO310, C1GALT1C1, C1GALT1-specific chaperone 1, C38H2-like protein 1, Core 1 beta3-galactosyltransferase-specific molecular chaperone, C38H2-L1, C1Gal-T2, C1GalT2, Core 1 beta3-Gal-T2)COSMC Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to COSMC.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
COSMC Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to COSMC.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 36 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 36 kDa
Purified recombinant protein of human COSMC
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
COSMC is a Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1)
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Subcellular Localization
Membrane
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Expression
Tissue_Specificity: Ubiquitously expressed. Abundantly expressed in salivary gland, stomach, small intestine, kidney, and testis and at intermediate levels in whole brain, cerebellum, spinal cord, thymus, spleen, trachea, lung, pancreas, ovary, and uterus. -
Isoforms & Post-Translational Modification
COSMC has an amino acid length of 318, molecular weight is 36382 Da.COSMC 的氨基酸个数为 318 个，分子量为 36382 Da。
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Subunit
Associates with core 1 beta-3-galactosyltransferase (C1GALT1), probably not with the soluble active form
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SwissProt ID
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Synonyms
COSMC, HSPC067, MSTP143, UNQ273/PRO310, C1GALT1C1, C1GALT1-specific chaperone 1, C38H2-like protein 1, Core 1 beta3-galactosyltransferase-specific molecular chaperone, C38H2-L1, C1Gal-T2, C1GalT2, Core 1 beta3-Gal-T2
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