CTDSP2 Antibody (YA8244)
(Synonyms: OS4; PSR2; SCP2)CTDSP2 Antibody (YA8244) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CTDSP2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:150-500 |
Product Details
CTDSP2 Antibody (YA8244) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CTDSP2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 30.5 kDa
Full length human recombinant protein of human CTDSP2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Envío
Shipping with blue ice.
Background
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Function
CTDSP2 is a Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver
Induction: In primary sarcomas -
Isoforms & Post-Translational Modification
O14595: 271 amino acids, molecular weight 30664 Da.
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Subunit
Monomer (By similarity)
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SwissProt ID
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Synonyms
OS4; PSR2; SCP2
Documentación
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