Delta-catenin Antibody (YA6543)
(Synonyms: ARM-repeat protein antibody; Catenin (cadherin associated protein) delta 2 antibody; catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) antibody; Catenin delta 2 antibody; Catenin delta-2 antibody; CTND2_HUMAN antibody; CTNND 2 antibody; Ctnnd2 antibody; Delta catenin antibody; Delta-catenin antibody; ARM-repeat protein antibody; Catenin (cadherin associated protein) delta 2 antibody; catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) antibody; Catenin delta 2 antibody; Catenin delta-2 antibody; CTND2_HUMAN antibody; CTNND 2 antibody; Ctnnd2 antibody; Delta catenin antibody; Delta-catenin antibody; GT 24 antibody; GT24 antibody; Neural plakophilin related arm repeat protein antibody; Neural plakophilin related armadillo repeat protein antibody; Neural plakophilin-related ARM-repeat protein antibody; Neural plakophilin-related, Neurojungin antibody; Neurojungin antibody; NPRAP antibody; T cell delta catenin antibody; )Delta-catenin Antibody (YA6543) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Delta-catenin.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IP, IHC-F
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IP
IP: Immunoprecipitation
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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|---|---|---|---|---|
| Dilution Ratio | 1:1000 | 1:200 | 1-2μg/sample | 1:200 |
Product Details
Delta-catenin Antibody (YA6543) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Delta-catenin.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat Predicted Reactivity: Cynomolgus monkey, Pig
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 135 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 135 kDa
Recombinant protein within Mouse Catenin delta-2 aa 1-100 / 1,247.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Delta-catenin is a Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses. Involved in the regulation of Wnt signaling. It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation. Functions as a transcriptional activator when bound to ZBTB33. May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules[1].
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Subcellular Localization
Nucleus,Cell junction, adherens junction,Cell projection, dendrite,Perikaryon
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Expression
Tissue_Specificity: Expressed in brain; highest expression is observed in fetal brain (PubMed:25807484) -
Isoforms & Post-Translational Modification
Q9UQB3 has 2 isomers: Q9UQB3-1: 132656 Da (predicted); Q9UQB3-2: 126529 Da (predicted).
O-glycosylated;Phosphorylated by CDK5 (By similarity). Phosphorylated by GSK3B (PubMed:19706605) -
Subunit
Binds to E-cadherin at a juxtamembrane site within the cytoplasmic domain (By similarity)
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SwissProt ID
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Synonyms
ARM-repeat protein antibody; Catenin (cadherin associated protein) delta 2 antibody; catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) antibody; Catenin delta 2 antibody; Catenin delta-2 antibody; CTND2_HUMAN antibody; CTNND 2 antibody; Ctnnd2 antibody; Delta catenin antibody; Delta-catenin antibody; ARM-repeat protein antibody; Catenin (cadherin associated protein) delta 2 antibody; catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) antibody; Catenin delta 2 antibody; Catenin delta-2 antibody; CTND2_HUMAN antibody; CTNND 2 antibody; Ctnnd2 antibody; Delta catenin antibody; Delta-catenin antibody; GT 24 antibody; GT24 antibody; Neural plakophilin related arm repeat protein antibody; Neural plakophilin related armadillo repeat protein antibody; Neural plakophilin-related ARM-repeat protein antibody; Neural plakophilin-related, Neurojungin antibody; Neurojungin antibody; NPRAP antibody; T cell delta catenin antibody;
Documentation
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