Desmocollin 1 Antibody (YA6544)
(Synonyms: Cadherin family member 1 antibody; CDHF1 antibody; Desmocollin1 antibody; Desmosomal glycoprotein 2/3 antibody; DG2/DG3 antibody; DSC 1 antibody; DSC1 antibody; )Desmocollin 1 Antibody (YA6544) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Desmocollin 1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Mouse, Rat
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Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:1000 |
Product Details
Desmocollin 1 Antibody (YA6544) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Desmocollin 1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityMouse, Rat
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Observed Molecular WeightObserved band size: 100/60kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 100 kDa
Synthetic peptide within Human Desmocollin 1 aa 795-894 / 894.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Desmocollin 1 is an A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation. Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood
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Subcellular Localization
Cell membrane,Cell junction, desmosome
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Expression
Tissue_Specificity: Strongly expressed in epidermis, less in lymph node and tongue -
Isoforms & Post-Translational Modification
Q08554 has 2 isomers: Q08554-1: 99987 Da (predicted); Q08554-2: 93835 Da (predicted).
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Subunit
Binds to JUP/plakoglobin
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SwissProt ID
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Synonyms
Cadherin family member 1 antibody; CDHF1 antibody; Desmocollin1 antibody; Desmosomal glycoprotein 2/3 antibody; DG2/DG3 antibody; DSC 1 antibody; DSC1 antibody;
Documentation