EHHADH Antibody (YA8059)(PBS only)

Cat. No.: HY-P88375A: Data Sheet User Guide for Antibodies
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EHHADH Antibody (YA8059) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EHHADH.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

EHHADH Antibody (YA8059) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EHHADH.

Host

Mouse

Molecular Weight

Predicted band size: 79.3 kDa

Species Reactivity

Human

SwissProt ID

Q08426

Immunogen

Human recombinant protein fragment corresponding to amino acids 496-723 of human EHHADH produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Peroxisomal trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities. Catalyzes two of the four reactions of the long chain fatty acids peroxisomal beta-oxidation pathway (By similarity). Can also use branched-chain fatty acids such as 2-methyl-2E-butenoyl-CoA as a substrate, which is hydrated into (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA (By similarity). Optimal isomerase for 2,5 double bonds into 3,5 form isomerization in a range of enoyl-CoA species (Probable). Also able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species (By similarity). With HSD17B4, catalyzes the hydration of trans-2-enoyl-CoA and the dehydrogenation of 3-hydroxyacyl-CoA, but with opposite chiral specificity (PubMed:15060085). Regulates the amount of medium-chain dicarboxylic fatty acids which are essential regulators of all fatty acid oxidation pathways (By similarity). Also involved in the degradation of long-chain dicarboxylic acids through peroxisomal beta-oxidation (PubMed:15060085)

Subcellular Localization：Peroxisome

Expression：
Tissue_Specificity: Liver and kidney. Strongly expressed in the terminal segments of the proximal tubule. Lower amounts seen in the brain

Isoforms & Post-Translational Modification：Q08426 has two isomers: Q08426-1: 79495 Da (predicted); Q08426-2: 69154 Da (predicted).
Acetylated, leading to enhanced enzyme activity

Subunit：Monomer

Synonyms

ECHD; FRTS3; L-PBE; LBFP; LBP; PBFE

Documentation

User Guide for Antibodies (1077 KB)