EXD1 Antibody (YA8510)
(Synonyms: EXDL1)EXD1 Antibody (YA8510) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EXD1.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
ICC/IF, FC
-
Reactivity :
Human
-
Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
EXD1 Antibody (YA8510) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EXD1.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Calculated Molecular Weight Predicted band size: 58.2 kDa
Full length human recombinant protein of human EXD1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
EXD1 is a RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease
-
Subcellular Localization
Cytoplasm
-
Isoforms & Post-Translational Modification
Q8NHP7 has three isomers: Q8NHP7-1: 58335 Da (predicted); Q8NHP7-2: 35585 Da (predicted); Q8NHP7-3: 64822 Da (predicted).
-
Subunit
Homodimer (By similarity)
-
SwissProt ID
-
Synonyms
EXDL1
Documentation
Powered by Bioz
