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FGF13 Antibody (YA8070)(PBS only)

(Synonyms: FGF-13; FGF2; FHF-2; FHF2)

FGF13 Antibody (YA8070) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGF13.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • FGF13 Antibody (YA8070)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:150-500

Product Details

Description

FGF13 Antibody (YA8070) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGF13.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 27.4 kDa
Immunogen

Full length human recombinant protein of human FGF13 produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    FGF13 is a Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons[1][2][3].

  • Subcellular Localization

    Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cell projection, filopodium,Cell projection, growth cone,Cell projection, dendrite,Cell membrane, sarcolemma,Cytoplasm

  • Expression


    Tissue_Specificity: Ubiquitously expressed. Predominantly expressed in the nervous system

  • Isoforms & Post-Translational Modification

    Q92913 has 5 isomers: Q92913-1: 27564 Da (predicted); Q92913-2: 21581 Da (predicted); Q92913-3: 28752 Da (predicted); Q92913-4: 22275 Da (predicted); Q92913-5: 25607 Da (predicted).
    May be phosphorylated

  • Subunit

    Interacts with SCN8A; regulates SCN8A activity (PubMed:15282281, PubMed:21566136, PubMed:33245860)

  • SwissProt ID

    Q92913

  • Synonyms

    FGF-13; FGF2; FHF-2; FHF2

FGF13 Antibody (YA8070)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • FGF13 Antibody (YA8070)(PBS only) Product Image