FGF13 Antibody (YA8070)(PBS only)

Art. -Nr.: HY-P88386A: Data Sheet User Guide for Antibodies
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FGF13 Antibody (YA8070) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGF13.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Größe		Verfügbarkeit
50 μL		Angebot einholen
100 μL		Angebot einholen

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Beschreibung

Beschreibung

FGF13 Antibody (YA8070) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGF13.

Host

Mouse

Molekulargewicht

Predicted band size: 27.4 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q92913

Immunogen

Full length human recombinant protein of human FGF13 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Reinheit	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Versand

Shipping with blue ice.

Background

Function：Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). Regulates voltage-gated sodium channel transport and function (PubMed:15282281, PubMed:33245860, PubMed:36696443). May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity)

Subcellular Localization：Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cell projection, filopodium,Cell projection, growth cone,Cell projection, dendrite,Cell membrane, sarcolemma,Cytoplasm

Expression：
Tissue_Specificity: Ubiquitously expressed. Predominantly expressed in the nervous system

Isoforms & Post-Translational Modification：Q92913 has 5 isomers: Q92913-1: 27564 Da (predicted); Q92913-2: 21581 Da (predicted); Q92913-3: 28752 Da (predicted); Q92913-4: 22275 Da (predicted); Q92913-5: 25607 Da (predicted).
May be phosphorylated

Subunit：Interacts with SCN8A; regulates SCN8A activity (PubMed:15282281, PubMed:21566136, PubMed:33245860)

Synonyms

FGF-13; FGF2; FHF-2; FHF2

Dokumentation

User Guide for Antibodies (1077 KB)