FOLR2 Antibody (YA8190)(PBS only)
(Synonyms: BETA-HFR; FBP; FR-BETA; FR-P3; PL-1)FOLR2 Antibody (YA8190) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FOLR2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
FOLR2 Antibody (YA8190) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FOLR2.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 29.1 kDa
Human recombinant protein fragment corresponding to amino acids 20-221 of human FOLR2 produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
FOLR2 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release
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Subcellular Localization
Cell membrane,Secreted
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Expression
Tissue_Specificity: Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues
Induction: Up-regulated by retinoic acid -
Isoforms & Post-Translational Modification
P14207: 255 amino acids, molecular weight 29280 Da.
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SwissProt ID
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Synonyms
BETA-HFR; FBP; FR-BETA; FR-P3; PL-1
Documentation
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