Haptoglobin Antibody
(Synonyms: Haptoglobin, Hp)Haptoglobin Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Haptoglobin.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
Haptoglobin Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Haptoglobin.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 45 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 38; 45 kDa
Purified recombinant protein of human Haptoglobin
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Haptoglobin is an As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity, and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Expressed by the liver and secreted in plasma. -
Isoforms & Post-Translational Modification
Haptoglobin has 2 isoforms, P00738-1: amino acid length is 406, molecular weight is 45205 Da (predicted); P00738-2: amino acid length is 347, molecular weight is 38452 Da (predicted).Haptoglobin 存在 2 个异构体，P00738-1：氨基酸个数为 406 个，分子量为 45205 Da (预测)；P00738-2：氨基酸个数为 347 个，分子量为 38452 Da (预测)。
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Subunit
Tetramer of two alpha and two beta chains; disulfide-linked.
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SwissProt ID
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Synonyms
Haptoglobin, Hp
Documentation
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