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  2. Primary Antibodies
  3. Monoclonal Antibodies Recombinant Antibodies
  4. HMGCL Antibody (YA3024)

HMGCL Antibody (YA3024)

Cat. No.: HY-P83279
User Guide for Antibodies Technical Support

HMGCL Antibody (YA3024) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HMGCL.

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사이즈 가격 재고 수량
20 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   견적 받기  
Synthetic products have potential research and development risk.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • 제품 설명

제품 설명

HMGCL Antibody (YA3024) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HMGCL.

Host

Rabbit

Clonality

Recombinant, Monoclonal

분자량
Predicted band size: 34 kDa;
Observed band size: 34 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human HMGCL

Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background
Function:Mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism
Subcellular Localization:Mitochondrion matrix; Peroxisome
Expression:
Tissue_specificity:Highest expression in liver. Expressed in pancreas, kidney, intestine, testis, fibroblasts and lymphoblasts. Very low expression in brain and skeletal muscle. The relative expression of isoform 2 (at mRNA level) is highest in heart (30%) , skeletal muscle (22%) , and brain (14%)
Isoforms & Post-Translational Modification:P35914 has 3 isomers: P35914-1: 34360 Da (predicted); P35914-2: 26910 Da (predicted); P35914-3: 20222 Da (predicted).
Subunit:Homodimer; disulfide-linked. Can also form homotetramers
Database
Research Field

Signal Transduction

Synonyms
3-hydroxymethyl-3-methylglutaryl-CoA lyase; HL
각종 서류

HMGCL Antibody (YA3024) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
HMGCL Antibody (YA3024)
Cat. No.:
HY-P83279
수량:
MCE Japan Authorized Agent: