Laminin beta 1 Antibody (YA4946)

Cat. No.: HY-P85254: Data Sheet User Guide for Antibodies
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Laminin beta 1 Antibody (YA4946) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Laminin beta 1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Laminin beta 1 Antibody (YA4946) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Laminin beta 1.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 198 kDa;

Species Reactivity

Human

SwissProt ID

P07942

Gene ID

3912 [NCBI]

Immunogen

Purified recombinant fragment of LAMB1 (aa31-270) expressed in E. Coli. The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Sensitivity	Endogenous	Purity	affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface

Subcellular Localization：Secreted, extracellular space, extracellular matrix, basement membrane

Subunit：Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma).

Synonyms

LAMB1; Laminin subunit beta-1; Laminin B1 chain; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta

Documentation

User Guide for Antibodies (1077 KB)