LLGL1 Antibody (YA3043)(PBS only)

Cat. No.: HY-P83298A: Data Sheet User Guide for Antibodies
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LLGL1 Antibody (YA3043) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LLGL1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

LLGL1 Antibody (YA3043) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LLGL1.

Host

Rabbit

Molecular Weight

Predicted band size: 115 kDa;

Observed band size: 115 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q15334

Gene ID

3996 [NCBI]

Immunogen

Recombinant protein of human LLGL1

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane

Subcellular Localization：Early endosome membrane; Golgi apparatus, trans-Golgi network membrane; Golgi apparatus membrane; Cell projection, axon; Cytoplasm, cytoskeleton

Expression：
Tissue_specificity:Expressed in brain, kidney, and muscle but is barely seen in heart and placenta. Down-regulated or lost in all cell lines and in most of the tumor samples analyzed. Loss was associated with advanced stage of the disease

Subunit：Associated with nonmuscle myosin II heavy chain. Interacts with PRKCI/aPKC, PARD6B/Par-6 and PARD6A.

Research Field

Neuroscience

Synonyms

DLG4; HUGL; LLGL; Lgl1; Mgl1; HUGL1; HUGL-1

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/a-431-cell.html [Content Brief]