MAPK6/ERK3 Antibody (YA3194)

Cat. No.: HY-P83449: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

MAPK6/ERK3 Antibody (YA3194) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAPK6/ERK3.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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MAPK6/ERK3 Antibody (YA3194) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

MAPK6/ERK3 Antibody (YA3194) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAPK6/ERK3.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 83 kDa;

Observed band size: 105 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q16659

Gene ID

5597 [NCBI]

Immunogen

A synthetic peptide of human MAPK6

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity)

Subcellular Localization：Cytoplasm; Nucleus

Expression：
Tissue_specificity:It is expressed at the highest levels in skeletal muscle, followed by the brain. It has also been found in fibroblasts of the heart, placenta, lungs, liver, pancreas, kidneys, and skin.

Subunit：Heterodimer with ERK4/MAPK4. Interacts with UBE3A; this interaction may be indirect and mediated by HERC2, possibly via HERC2 interaction with NEURL4

Database

Entrez Gene: 5597 Human ; 50772 Mouse ; 58840 Rat

SwissProt: Q16659 Human ; Q61532 Mouse ; P27704 Rat

OMIM: 602904 Human

Research Field

Signal Transduction

Synonyms

ERK3; PRKM6; p97MAPK; HsT17250; ERK-3

Documentation

Select Batch:

Data Sheet (232 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

MAPK6/ERK3 Antibody (YA3194) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MAPK6/ERK3 Antibody (YA3194)

MAPK6/ERK3 Antibody (YA3194) Featured Recommendations:

Product Detail

Background

Documentation

MAPK6/ERK3 Antibody (YA3194) Related Classifications

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