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  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. MAPK6/ERK3 Antibody (YA3194)

MAPK6/ERK3 Antibody (YA3194)

Cat. No.: HY-P83449
COA
SDS
User Guide for Antibodies Technical Support

MAPK6/ERK3 Antibody (YA3194) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAPK6/ERK3.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Descripciòn

Descripciòn

MAPK6/ERK3 Antibody (YA3194) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAPK6/ERK3.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Peso molecular
Predicted band size: 83 kDa;
Observed band size: 105 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human MAPK6
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:5000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
Sensitivity Endogenous Pureza Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Background
Function：Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity)
Subcellular Localization：Cytoplasm; Nucleus
Expression：
Tissue_specificity:It is expressed at the highest levels in skeletal muscle, followed by the brain. It has also been found in fibroblasts of the heart, placenta, lungs, liver, pancreas, kidneys, and skin.
Subunit：Heterodimer with ERK4/MAPK4. Interacts with UBE3A; this interaction may be indirect and mediated by HERC2, possibly via HERC2 interaction with NEURL4
Database

Entrez Gene: 5597 Human ; 50772 Mouse ; 58840 Rat

SwissProt: Q16659 Human ; Q61532 Mouse ; P27704 Rat

OMIM: 602904 Human

Research Field

Signal Transduction
Synonyms
ERK3; PRKM6; p97MAPK; HsT17250; ERK-3
Documentación
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

MAPK6/ERK3 Antibody (YA3194) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
MAPK6/ERK3 Antibody (YA3194)
Cat. No.:
HY-P83449
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