MED28 Antibody (YA8217)(PBS only)
(Synonyms: 1500003D12Rik; EG1; magicin)MED28 Antibody (YA8217) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MED28.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
MED28 Antibody (YA8217) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MED28.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 19.3 kDa
Full length human recombinant protein of human MED28 produced in E.coli.
Affinity purified
Non-conjugated
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MED28 component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways
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Subcellular Localization
Nucleus,Cytoplasm,Membrane
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Expression
Tissue_Specificity: Widely expressed. Highly expressed in vascular tissues such as placenta, testis and liver
Induction: Up-regulated by endothelial cells when exposed to tumor conditional media -
Isoforms & Post-Translational Modification
Q9H204: 178 amino acids, molecular weight 19520 Da.
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Subunit
Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11
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SwissProt ID
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Synonyms
1500003D12Rik; EG1; magicin
Documentation
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