Copy Link Print Information

NGDN Antibody (YA8755)(PBS only)

(Synonyms: C14orf120; CANu1; LCP5; lpd-2; NGD)

NGDN Antibody (YA8755) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NGDN.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • NGDN Antibody (YA8755)(PBS only) Product Image
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Service
Data Download
Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:150-500

Product Details

Description

NGDN Antibody (YA8755) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NGDN.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 35.7 kDa
Immunogen

Full length human recombinant protein of human NGDN produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    NGDN is a Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Its dissociation from the complex determines the transition from state pre-A1 to state pre-A1*. Inhibits mRNA translation in a cytoplasmic polyadenylation element (CPE)-dependent manner[1].

  • Subcellular Localization

    Nucleus,Nucleus, nucleolus,Chromosome, centromere,Cytoplasm,Cell projection, axon,Cell projection, dendrite,Cell projection, filopodium

  • Isoforms & Post-Translational Modification

    Q8NEJ9 has two isomers: Q8NEJ9-1: 35894 Da (predicted); Q8NEJ9-2: 35250 Da (predicted).

  • Subunit

    Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797)

  • SwissProt ID

    Q8NEJ9

  • Synonyms

    C14orf120; CANu1; LCP5; lpd-2; NGD

NGDN Antibody (YA8755)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00

Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • NGDN Antibody (YA8755)(PBS only) Product Image
    1/16
  • NGDN Antibody (YA8755)(PBS only) Product Image