PAPSS2 Antibody (YA8721)
(Synonyms: ATPSK2; BCYM4; SK2)PAPSS2 Antibody (YA8721) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PAPSS2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:150-500 |
Product Details
PAPSS2 Antibody (YA8721) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PAPSS2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 69.3 kDa
Human recombinant protein fragment corresponding to amino acids 1-247 of human PAPSS2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PAPSS2 is a Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases. In mammals, PAPS is the sole source of sulfate while APS appears to only be an intermediate in the sulfate-activation pathway. Plays indirectly an important role in skeletogenesis during postnatal growth[1][2][3][4][5].
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Expression
Tissue_Specificity: Expressed in cartilage and adrenal gland -
Isoforms & Post-Translational Modification
O95340 has two isomers: O95340-1: 69501 Da (predicted); O95340-2: 69970 Da (predicted).
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SwissProt ID
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Synonyms
ATPSK2; BCYM4; SK2
Documentation
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