PDCD2 Antibody
(Synonyms: RP8, ZMYND7)PDCD2 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PDCD2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), 0.05% NaN3, 40% Glycerol
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-1000 | 1:50-100 |
Product Details
PDCD2 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PDCD2.
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Host Rabbit
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Clonality polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 39 kDa;Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 39 kDa
Synthetic peptide of human PDCD2
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), 0.05% NaN3, 40% Glycerol
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PDCD2 is a Chaperone for ribosomal protein uS5; cotranslationally associates with uS5 and accompanies the ribosomal protein to assembly sites in the nucleus; appears to function redundantly to PDCD2L
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Subcellular Localization
Nucleus, nucleolus; Cytoplasm, cytosol
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Expression
Tissue_Specificity: Ubiquitous. -
Isoforms & Post-Translational Modification
PDCD2 has 5 isoforms, Q16342-1: amino acid length is 344, molecular weight is 38592 Da (predicted); Q16342-2: amino acid length is 195, molecular weight is 22230 Da (predicted); Q16342-3: amino acid length is 311, molecular weight is 35290 Da (predicted); Q16342-4: amino acid length is 228, molecular weight is 25532 Da (predicted); Q16342-5: amino acid length is 188, molecular weight is 21299 Da (predicted).被 PRKN 泛素化,促进蛋白酶体降解PDCD2 存在 5 个异构体,Q16342-1:氨基酸个数为 344 个,分子量为 38592 Da (预测);Q16342-2:氨基酸个数为 195 个,分子量为 22230 Da (预测);Q16342-3:氨基酸个数为 311 个,分子量为 35290 Da (预测);Q16342-4:氨基酸个数为 228 个,分子量为 25532 Da (预测);Q16342-5:氨基酸个数为 188 个,分子量为 21299 Da (预测)。Ubiquitinated by PRKN, promoting proteasomal degradation
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Subunit
Interacts with small ribosomal subunit protein RPS2/uS5; the interaction is direct, occurs cotranslationally, and serves to chaperone uS5 to assembly sites in the nucleus
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SwissProt ID
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Synonyms
RP8, ZMYND7
Documentation