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  4. Monoclonal Antibodies Recombinant Antibodies Modification Specific Antibodies
  5. Phospho-KIF22 (Ser427) Antibody (YA2498)

Phospho-KIF22 (Ser427) Antibody (YA2498)

Cat. No.: HY-P82753
User Guide for Antibodies Technical Support

Phospho-KIF22 (Ser427) Antibody (YA2498) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-KIF22 (Ser427).

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Tamaño Precio Stock Cantidad
20 μL Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Obtener un presupuesto  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Descripciòn

Descripciòn

Phospho-KIF22 (Ser427) Antibody (YA2498) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-KIF22 (Ser427).
Host

Rabbit
Clonality

Recombinant, Monoclonal
Peso molecular
Predicted band size: 73 kDa;
Observed band size: 73 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser427 of human KIF22 aa421-434.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Pureza Affinity Purified
Conjugation Non-conjugated Modification Phosphorylated
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Background
Function：Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA (By similarity). Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells (PubMed:25743205)
Subcellular Localization：Nucleus; Cytoplasm, cytoskeleton
Expression：
Tissue_specificity:It is expressed in bone, cartilage, joint capsule, ligament, skin, and primary cultured chondrocytes.
Isoforms & Post-Translational Modification：Q14807 has 2 isomers: Q14807-1: 73262 Da (predicted); Q14807-2: 66307 Da (predicted).
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation
Subunit：Interacts with FAM83D (PubMed:18485706). Interacts with SIAH1 (PubMed:11146551)
Database

Entrez Gene: 3835 Human

SwissProt: Q14807 Human

OMIM: 603546 Human

Research Field

Signal Transduction
Synonyms
KIF22; KID; KNSL4; Kinesin-like protein KIF22; Kinesin-like DNA-binding protein; Kinesin-like protein 4
Documentación
User Guide for Antibodies (1077 KB)

Phospho-KIF22 (Ser427) Antibody (YA2498) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
Phospho-KIF22 (Ser427) Antibody (YA2498)
Cat. No.:
HY-P82753
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