PLIN5 Antibody (YA7909)

Cat. No.: HY-P88225: Data Sheet User Guide for Antibodies
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PLIN5 Antibody (YA7909) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLIN5.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

PLIN5 Antibody (YA7909) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLIN5.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 51.2 kDa

Species Reactivity

Human

SwissProt ID

Q00G26

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-463 of human PLIN5 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-800

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity)

Subcellular Localization：Lipid droplet,Cytoplasm,Mitochondrion

Expression：
Tissue_Specificity: Expressed in skeletal muscle, liver, heart and kidney
Induction: Increased by endurance and sprint interval training

Isoforms & Post-Translational Modification：Q00G26: 463 amino acids, molecular weight 50791 Da.

Subunit：Homooligomer

Synonyms

LSDA5; LSDP5; MLDP; OXPAT

Documentation

User Guide for Antibodies (1077 KB)