PMF 1 Antibody (YA3165)
(Synonyms: Polyamine-modulated factor 1)PMF 1 Antibody (YA3165) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PMF 1.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IP
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IP
IP: Immunoprecipitation
|
|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:20 |
Product Details
PMF 1 Antibody (YA3165) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PMF 1.
-
Host Rabbit
-
Clonality Recombinant, Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 23 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 23 kDa
Entrez Gene: 100527963 Human ; 11243 Human ; 67037 Mouse ; 681050 Rat
SwissProt: Q6P1K2 Human ; Q9CPV5 Mouse ;
OMIM: 609176 Human
Recombinant protein of human PMF-1
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
PMF 1 is a Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT
-
Subcellular Localization
Nucleus; Chromosome, centromere, kinetochore
-
Expression
Tissue_specificity:Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver
Induction:By polyamine analogs in analog-sensitive H157 cells -
Isoforms & Post-Translational Modification
Q6P1K2 has 6 isomers: Q6P1K2-1: 23339 Da (predicted); Q6P1K2-2: 22946 Da (predicted); Q6P1K2-3: 18977 Da (predicted); Q6P1K2-4: 19238 Da (predicted); Q6P1K2-5: 24032 Da (predicted); Q6P1K2-6: 20230 Da (predicted).
-
Subunit
Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Interacts with COPS7A. Interacts via its coiled-coil domain with the leucine-zipper domain of NFE2L2. The interaction with NFE2L2 is required for the transcriptional regulation of SSAT
-
SwissProt ID
-
Synonyms
Polyamine-modulated factor 1
-
Research Field
-
Documentation
Powered by Bioz
