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Cat. No.: HY-P86275

PPIL1 Antibody (YA5967)

Name: PPIL1 Antibody (YA5967)
Brand: MedChemExpress
SKU: HY-P86275
Availability: PreOrder

(Synonyms: PPIL1; CYPL1; CGI-124; UNQ2425/PRO4984; Peptidyl-prolyl cis-trans isomerase-like 1 ; PPIase; Rotamase PPIL1; )

PPIL1 Antibody (YA5967) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPIL1.

For research use only. We do not sell to patients.

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Price

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	FC 1
Dilution Ratio	1:1000-5000	100-300

Description

PPIL1 Antibody (YA5967) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPIL1.

Host Rabbit
Clonality Monoclonal
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 19 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Purification

Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

PPIL1 is involved in pre-mRNA splicing as component of the spliceosome. PPIases accelerate the folding of proteins. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Catalyzes prolyl peptide bond isomerization in CDC40/PRP17. Plays an important role in embryonic brain development; this function is independent of its isomerase activity^[1]^[2]^[3]^[4]^[5].
Subcellular Localization

Nucleus
Expression

Tissue_specificity:Ubiquitous, with the most abundant expression in heart and skeletal muscle
Subunit

Identified in the spliceosome C complex (PubMed:11991638, PubMed:28076346, PubMed:28502770). Interacts with SNW1/SKIP (PubMed:16595688, PubMed:20368803, PubMed:33220177). Interacts with CDC40/PRP17; this interaction leads to CDC40 isomerization (PubMed:33220177). Interacts with RBM22 (PubMed:33220177)
SwissProt ID

Q5TDC9
Gene ID

51645 [NCBI]
Synonyms

PPIL1; CYPL1; CGI-124; UNQ2425/PRO4984; Peptidyl-prolyl cis-trans isomerase-like 1 ; PPIase; Rotamase PPIL1;