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PRRT2 Antibody (YA8050)(PBS only)

(Synonyms: BFIC2; BFIS2; DSPB3; DYT10; EKD1; FICCA; ICCA; IFITMD1; PKC)

PRRT2 Antibody (YA8050) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRRT2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • PRRT2 Antibody (YA8050)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:2000-2500

Product Details

Description

PRRT2 Antibody (YA8050) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRRT2.

  • Host Mouse
  • Species Reactivity
    Human
Immunogen

Human recombinant protein fragment corresponding to amino acids 152-268 of human PRRT2 produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PRRT2 is an As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and down-regulate short-term facilitation

  • Subcellular Localization

    Cell membrane,Presynaptic cell membrane,Synapse,Cell projection, axon,Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane,Postsynaptic density membrane,Cell projection, dendritic spine

  • Isoforms & Post-Translational Modification

    Q7Z6L0 has three isomers: Q7Z6L0-1: 34945 Da (predicted); Q7Z6L0-2: 40228 Da (predicted); Q7Z6L0-3: 30653 Da (predicted).

  • Subunit

    Component of the outer core of AMPAR complex (PubMed:25915028)

  • SwissProt ID

    Q7Z6L0

  • Synonyms

    BFIC2; BFIS2; DSPB3; DYT10; EKD1; FICCA; ICCA; IFITMD1; PKC

PRRT2 Antibody (YA8050)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • PRRT2 Antibody (YA8050)(PBS only) Product Image
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  • PRRT2 Antibody (YA8050)(PBS only) Product Image