Rab1A Antibody (YA6750)
(Synonyms: GTP binding protein RAB 1A antibody; mKIAA3012 antibody; RAB 1 antibody; Rab 1A antibody; RAB1 antibody; RAB1, member RAS oncogene family antibody; Rab1A antibody; RAB1A member RAS oncogene family antibody; RAB1A_HUMAN antibody; Ras related protein Rab 1A antibody; GTP binding protein RAB 1A antibody; mKIAA3012 antibody; RAB 1 antibody; Rab 1A antibody; RAB1 antibody; RAB1, member RAS oncogene family antibody; Rab1A antibody; RAB1A member RAS oncogene family antibody; RAB1A_HUMAN antibody; Ras related protein Rab 1A antibody; Ras-associated protein RAB1 antibody; Ras-related protein Rab-1A antibody; YPT1 antibody; YPT1 related protein antibody; YPT1-related protein antibody; )Rab1A Antibody (YA6750) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rab1A.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:2000 | 1:200-1:1000 | 1:100-1:200 | 1:1000 |
Product Details
Rab1A Antibody (YA6750) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rab1A.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 23 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 23 kDa
Synthetic peptide within human Rab1A aa 156-205 / 205.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Rab1A is a The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Required to modulate the compacted morphology of the Golgi. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport[1][2][3][4][5].
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Subcellular Localization
Golgi apparatus,Endoplasmic reticulum,Early endosome,Cytoplasm, cytosol,Membrane,Melanosome
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Isoforms & Post-Translational Modification
P62820 has three isomers: P62820-1: 22678 Da (predicted); P62820-2: 15331 Da (predicted); P62820-3: 13903 Da (predicted).
Phosphorylated by CDK1 kinase during mitosis丨(Microbial infection) Phosphocholinated at Ser-79 by L丨(Microbial infection) Glycosylated by S丨Ubiquitinated via 'Lys-11'-linked ubiquitination on Lys-49 and Lys-61; impairing the recruitment of guanosine diphosphate (GDP) dissociation inhibitor 1/GDI1 -
Subunit
May interact with YIPF5 (By similarity)
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SwissProt ID
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Synonyms
GTP binding protein RAB 1A antibody; mKIAA3012 antibody; RAB 1 antibody; Rab 1A antibody; RAB1 antibody; RAB1, member RAS oncogene family antibody; Rab1A antibody; RAB1A member RAS oncogene family antibody; RAB1A_HUMAN antibody; Ras related protein Rab 1A antibody; GTP binding protein RAB 1A antibody; mKIAA3012 antibody; RAB 1 antibody; Rab 1A antibody; RAB1 antibody; RAB1, member RAS oncogene family antibody; Rab1A antibody; RAB1A member RAS oncogene family antibody; RAB1A_HUMAN antibody; Ras related protein Rab 1A antibody; Ras-associated protein RAB1 antibody; Ras-related protein Rab-1A antibody; YPT1 antibody; YPT1 related protein antibody; YPT1-related protein antibody;
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