RhoGDI Antibody (YA1863)(PBS only)

Cat. No.: HY-P82118A: Data Sheet User Guide for Antibodies
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RhoGDI Antibody (YA1863) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RhoGDI.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

RhoGDI Antibody (YA1863) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RhoGDI.

Host

Rabbit

분자량

Predicted band size: 23 kDa;

Observed band size: 26 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P52565

Gene ID

396 [NCBI]

Immunogen

A synthetic peptide of human RhoGDI aa125-138.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1

Subcellular Localization：Cytoplasm

Isoforms & Post-Translational Modification：P52565 has 2 isomers: P52565-1: 23207 Da (predicted); P52565-2: 18233 Da (predicted).

Subunit：Interacts with FER (PubMed:21122136). Forms a heterodimer with RAC1 (PubMed:23434736).

Research Field

Signal Transduction

Synonyms

ARHGDIA; GDIA1; Rho GDP-dissociation inhibitor 1; Rho GDI 1; Rho-GDI alpha

각종 서류

User Guide for Antibodies (1077 KB)