RIM2 Antibody (YA7037)
(Synonyms: KIAA0751 antibody; Non small cell lung cancer RimL3a protein antibody; Non small cell lung cancer RimL3c protein antibody; OBOE antibody; Protein regulating synaptic membrane exocytosis 2 antibody; Rab-3-interacting molecule 2 antibody; Rab-3-interacting protein 3 antibody; Rab3 interacting molecule 2 antibody; RAB3IP3 antibody; Regulating synaptic membrane exocytosis 2 antibody)RIM2 Antibody (YA7037) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RIM2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IP
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Reactivity :
Human, Rat
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Formulation:
Supplied in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|---|---|
| Dilution Ratio | 1:100-1:1000 | 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) | 1:50-500 | 1:50-500 |
Product Details
RIM2 Antibody (YA7037) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RIM2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 160kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 160kDa
peptide
Endogenous
Protein A affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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Storage & Stability
Stored at 2-8°C for 1 year, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
RIM2 is a Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes[1].
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Subcellular Localization
Cell membrane,Synapse,Presynaptic cell membrane
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Expression
Tissue_Specificity: Widely expressed (PubMed:32470375). Expressed in melanocytes (PubMed:23999003). In fetal tissues, predominantly expressed in the brain (PubMed:32470375). In the retina, expressed in the outer plexiform layer (at protein level) (PubMed:32470375). In the cerebellum, expressed in Purkinje cells (at protein level) (PubMed:32470375). In the pancreas, expressed in Langerhans islets (at protein level) (PubMed:32470375) -
Isoforms & Post-Translational Modification
Q9UQ26 has 8 isomers: Q9UQ26-6: 160403 Da (predicted); Q9UQ26-1: 135250 Da (predicted); Q9UQ26-2: 119057 Da (predicted); Q9UQ26-3: 132670 Da (predicted); Q9UQ26-4: 91941 Da (predicted); Q9UQ26-5: 94172 Da (predicted); Q9UQ26-7: 30972 Da (predicted); Q9UQ26-8: 153363 Da (predicted).
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Subunit
Interacts with RAB3A and RAB3B that have been activated by GTP-binding
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SwissProt ID
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Synonyms
KIAA0751 antibody; Non small cell lung cancer RimL3a protein antibody; Non small cell lung cancer RimL3c protein antibody; OBOE antibody; Protein regulating synaptic membrane exocytosis 2 antibody; Rab-3-interacting molecule 2 antibody; Rab-3-interacting protein 3 antibody; Rab3 interacting molecule 2 antibody; RAB3IP3 antibody; Regulating synaptic membrane exocytosis 2 antibody
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