RPAIN Antibody (YA8797)
(Synonyms: HRIP; RIP)RPAIN Antibody (YA8797) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to RPAIN.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
RPAIN Antibody (YA8797) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to RPAIN.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Full length human recombiant protein of human RPAIN produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
RPAIN mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism
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Subcellular Localization
Cytoplasm,Nucleus,Nucleus, PML body
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Expression
Tissue_Specificity: Widely expressed. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain, heart, leukocytes, colon, intestine, ovary, testis, prostate, thymus and spleen -
Isoforms & Post-Translational Modification
Q86UA6 has 9 isomers: Q86UA6-1: 24770 Da (predicted); Q86UA6-2: 19712 Da (predicted); Q86UA6-3: 16511 Da (predicted); Q86UA6-4: 16810 Da (predicted); Q86UA6-5: 12385 Da (predicted); Q86UA6-6: 12309 Da (predicted); Q86UA6-7: 12398 Da (predicted); Q86UA6-8: 26207 Da (predicted); Q86UA6-9: 17103 Da (predicted).
Sumoylated -
Subunit
Interacts with the RPA1 subunit of RPA complex
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SwissProt ID
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Synonyms
HRIP; RIP
Documentation
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