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SKIL (SnoN) Antibody (YA8254)(PBS only)

(Synonyms: SNO; SnoA; SnoI; SnoN)

SKIL (SnoN) Antibody (YA8254) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SKIL (SnoN).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • SKIL (SnoN) Antibody (YA8254)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:150-500

Product Details

Description

SKIL (SnoN) Antibody (YA8254) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SKIL (SnoN).

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 76.8 kDa
Immunogen

Human recombinant protein fragment corresponding to amino acids 307-684 of human SKIL produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    SKIL may have regulatory role in cell division or differentiation in response to extracellular signals

  • Expression


    Tissue_Specificity: Isoform SNON and isoform SNOA are widely expressed. Highest expression is found in skeletal muscle, followed by placenta and lung. Lowest expression in heart, brain and pancreas. Isoform SNOI expression is restricted to skeletal muscle

  • Isoforms & Post-Translational Modification

    P12757 has 5 isomers: P12757-1: 76976 Da (predicted); P12757-2: 46335 Da (predicted); P12757-3: 71767 Da (predicted); P12757-4: 44203 Da (predicted); P12757-5: 74784 Da (predicted).
    Ubiquitinated by RNF111 and ARK2C, promoting proteasomal degradation, leading to enhance the BMP-Smad signaling

  • Subunit

    Interacts with CPNE4 (via VWFA domain) (By similarity)

  • SwissProt ID

    P12757

  • Synonyms

    SNO; SnoA; SnoI; SnoN

SKIL (SnoN) Antibody (YA8254)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • SKIL (SnoN) Antibody (YA8254)(PBS only) Product Image
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  • SKIL (SnoN) Antibody (YA8254)(PBS only) Product Image