STEAP3 Antibody
(Synonyms: TSAP6, STEAP3, Metalloreductase STEAP3, Dudulin-2, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, pHyde, hTSAP6, hpHyde)STEAP3 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to STEAP3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol and 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:5000-8000 |
Product Details
STEAP3 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to STEAP3.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 55 kDa
Synthetic peptide of human STEAP3 (aa 151-200).
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol and 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
STEA3 is an integrated membrane protein that functions as a NADPH-dependent iron chelate reductase, using NADPH on one side of the membrane to reduce Fe3+ chelates bound to the other side.
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Subcellular Localization
Endosome membrane; Multi-pass membrane protein
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Expression
Tissue specificity: Expressed in adult bone marrow, placenta, liver, skeletal muscle and pancreas. Down-regulated in hepatocellular carcinoma.
Induction: By p53/TP53. -
Isoforms & Post-Translational Modification
STEAP3 exists in four isomers: Q658P3-1 (488 amino acids, predicted molecular weight 54,601 Da); Q658P3-2 (498 amino acids, predicted molecular weight 55,652 Da); Q658P3-3 (487 amino acids, predicted molecular weight 54,472 Da); and Q658P3-4 (456 amino acids, predicted molecular weight 50,499 Da).
It can be cleaved by RHBDL4/RHBDD1 protein hydrolysis. RHBDL4/RHBDD1-induced cleavage occurs at multiple sites and is independent of glycosylation. Glycosylation modification. -
Subunit
Homodimer. Interacts with BNIP3L, MYT1, RHBDL4/RHBDD1 and TCTP.
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SwissProt ID
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Synonyms
TSAP6, STEAP3, Metalloreductase STEAP3, Dudulin-2, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, pHyde, hTSAP6, hpHyde
Documentation
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