Syntaxin 4 Antibody (YA9723)
(Synonyms: NY REN 31 antigen, p35 2, PLACENTAL, Renal carcinoma antigen NY REN 31, Renal carcinoma antigen NY-REN-31, Stx4, STX4_HUMAN, STX4A, Syntaxin 4, syntaxin 4A (placental))Syntaxin 4 Antibody (YA9723) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Syntaxin 4.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P, IF-Tissue
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|---|---|
| Dilution Ratio | 1:1000 | 1:200 | 1:1000 |
Product Details
Syntaxin 4 Antibody (YA9723) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Syntaxin 4.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Calculated Molecular Weight Predicted band size: 34 kDa;
Recombinant protein of human Syntaxin 4 (aa 1-275).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Syntaxin 4 is a Plasma membrane t-SNARE that mediates docking of transport vesicles (By similarity). Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane (By similarity). In neurons, recruited at neurite tips to membrane domains rich in the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) which promotes neurite tip surface expression of the dopamine transporter SLC6A3/DAT by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane (By similarity). Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones (By similarity). Required for normal hearing[1].
-
Subcellular Localization
Cell membrane; Cell projection, neuron projection; Cell projection, stereocilium; Cytoplasm, perinuclear region
-
Expression
Tissue_Specificity: Expressed in neutrophils and neutrophil-differentiated HL-60 cells. Expression in neutrophils increases with differentiation. -
Isoforms & Post-Translational Modification
Syntaxin 4 has 2 isoforms, Q12846-1: amino acid length is 297, molecular weight is 34180 Da (predicted); Q12846-2: amino acid length is 295, molecular weight is 33841 Da (predicted).
-
Subunit
Component of the SNARE complex composed of STX4, SNAP23 and VAMP7 that interacts with SYT7 during lysosomal exocytosis.
-
SwissProt ID
-
Synonyms
NY REN 31 antigen, p35 2, PLACENTAL, Renal carcinoma antigen NY REN 31, Renal carcinoma antigen NY-REN-31, Stx4, STX4_HUMAN, STX4A, Syntaxin 4, syntaxin 4A (placental)
Documentation
Powered by Bioz
