TBR2 Antibody (YA6794)
(Synonyms: eomes EOMES_HUMAN Eomesodermin Eomesodermin homolog t box brain 2 T-box brain protein 2 T-brain-2 Tbr 2 TBR-2)
Based on 1 Customer Validation
TBR2 Antibody (YA6794) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TBR2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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|---|---|---|---|
| Dilution Ratio | 1:1000 | 1:5000 | 1:500 |
Product Details
TBR2 Antibody (YA6794) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TBR2.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse Predicted Reactivity: Cynomolgus monkey,Pig
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 73/85 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 73 kDa
Recombinant protein within human TBR2 aa 1-300.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TBR2 functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Required for differentiation and migration of unipolar dendritic brush cells. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes[1][2][3].
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Expressed in CD8+ T-cells
Induction: Up-regulated in CD8+ T-cells simultaneously stimulated with TGFB1 and IL4/interleukin-4 -
Isoforms & Post-Translational Modification
O95936 has four isomers: O95936-1: 72732 Da (predicted); O95936-2: 47067 Da (predicted); O95936-3: 45983 Da (predicted); O95936-4: 74852 Da (predicted).
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SwissProt ID
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Synonyms
eomes EOMES_HUMAN Eomesodermin Eomesodermin homolog t box brain 2 T-box brain protein 2 T-brain-2 Tbr 2 TBR-2
Documentation
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Data Sheet (231 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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User Guide for Antibodies (1077 KB)
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