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TCEA1 Antibody (YA2158)(PBS only)

(Synonyms: SII; TCEA; TF2S; GTF2S; TFIIS)

TCEA1 Antibody (YA2158) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TCEA1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human, Mouse, Rat, Monkey

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • TCEA1 Antibody (YA2158)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

TCEA1 Antibody (YA2158) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TCEA1.

  • Host Rabbit
  • Species Reactivity
    Human, Mouse, Rat, Monkey
  • Observed Molecular Weight
    Observed band size: 34 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 34 kDa
Immunogen

Recombinant protein of human TCEA1

Purification

Affinity Purified

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    TCEA1 is a Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus

  • Subcellular Localization

    Nucleus

  • Isoforms & Post-Translational Modification

    P23193 has 2 isomers: P23193-1: 33970 Da (predicted); P23193-2: 31664 Da (predicted).

  • Subunit

    Associates with UBR5 and forms a transcription regulatory complex made of CDK9, Pol II, UBR5 and TCEA1/TFIIS (PubMed:21127351).

  • SwissProt ID

    P23193

  • Gene ID
    6917 [NCBI]
  • Synonyms

    SII; TCEA; TF2S; GTF2S; TFIIS

  • Research Field

    Epigenetics and Nuclear Signaling

TCEA1 Antibody (YA2158)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • TCEA1 Antibody (YA2158)(PBS only) Product Image