THOP1 (Thimet Oligopeptidase) Antibody (YA8132)

Cat. No.: HY-P88448: Ficha de datos User Guide for Antibodies
FAQs
Technical Support

THOP1 (Thimet Oligopeptidase) Antibody (YA8132) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to THOP1 (Thimet Oligopeptidase).

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

* Seleccione Cantidad antes de agregar artículos.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

THOP1 (Thimet Oligopeptidase) Antibody (YA8132) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to THOP1 (Thimet Oligopeptidase).

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 78.7 kDa

Species Reactivity

Human

SwissProt ID

P52888

Immunogen

Full length human recombinant protein of human THOP1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000-3000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Solution

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation (PubMed:17251185, PubMed:7639763). Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments (PubMed:17251185, PubMed:7639763). Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1 (By similarity)

Subcellular Localization：Cytoplasm

Isoforms & Post-Translational Modification：P52888 has two isomers: P52888-1: 78840 Da (predicted); P52888-2: 28908 Da (predicted).

Subunit：Monomer

Synonyms

EP24.15; MEPD_HUMAN; MP78; TOP

Documentación

User Guide for Antibodies (1077 KB)