2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. TIMM50 Antibody (YA2390)

TIMM50 Antibody (YA2390)

Art. -Nr.: HY-P82645
COA
SDS
User Guide for Antibodies Technical Support

TIMM50 Antibody (YA2390) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TIMM50.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Beschreibung

Beschreibung

TIMM50 Antibody (YA2390) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TIMM50.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molekulargewicht
Predicted band size: 40 kDa;
Observed band size: 36 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human TIMM50 aa25-77/353.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:2000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
Sensitivity Endogenous Reinheit Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Versand

Shipping with blue ice.
Background
Function：Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (PubMed:30190335, PubMed:38828998). Has some phosphatase activity in vitro; however such activity may not be relevant in vivo; May participate in the release of snRNPs and SMN from the Cajal body
Subcellular Localization：Mitochondrion inner membrane; Single-pass membrane protein; Nucleus speckle
Expression：
Tissue_specificity:Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level)
Isoforms & Post-Translational Modification：Q3ZCQ8 has 3 isomers: Q3ZCQ8-1: 39646 Da (predicted); Q3ZCQ8-2: 50465 Da (predicted); Q3ZCQ8-3: 27579 Da (predicted).
Subunit：Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50; within this complex, directly interacts with TIMM23 (PubMed:15044455, PubMed:30190335, PubMed:38828998). The complex interacts with the TIMM44 component of the PAM complex and with DNAJC15 (PubMed:23263864)
Database

Entrez Gene: 92609 Human ; 66525 Mouse ; 685725 Rat

SwissProt: Q3ZCQ8 Human ; Q9D880 Mouse ;

OMIM: 617698 Human

Research Field

-
Synonyms
TIM50; TIM50L; TIMM50
Dokumentation
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

TIMM50 Antibody (YA2390) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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TIMM50 Antibody (YA2390)
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