TOM70 Antibody (YA6808)

Cat. No.: HY-P87115: Data Sheet COA
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TOM70 Antibody (YA6808) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TOM70.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TOM70 Antibody (YA6808) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TOM70.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 67 kDa;

Observed band size: 67 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat, Monkey

SwissProt ID

O94826

Gene ID

9868 [NCBI]

Immunogen

Recombinant protein within human TOM70 aa 86-608 / 608.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:20000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100
FC FC: Flow Cytometry	1:1000
IP IP: Immunoprecipitation	1-2μg/sample

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Acts as a receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) (PubMed:12526792). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed:12526792, PubMed:35025629). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (PubMed:20628368, PubMed:25609812, PubMed:32728199). Upon Sendai virus infection, recruits HSP90AA1:IRF3:BAX in mitochondrion and the complex induces apoptosis (PubMed:25609812)

Subcellular Localization：Mitochondrion outer membrane

Isoforms & Post-Translational Modification：O94826: 608 amino acids, molecular weight 67455 Da.

Subunit：Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70) (PubMed:18331822)

Synonyms

FLJ9047 antibody; Mitochondrial import receptor subunit TOM70 antibody; Mitochondrial precursor proteins import receptor antibody; TOM70 antibody; TOM70_HUMAN antibody; Tomm70a antibody; Translocase of outer membrane 70 kDa subunit antibody; Translocase of outer membrane TOM70 antibody; Translocase of outer mitochondrial membrane 70 homolog A antibody;

Documentation

Select Batch:

Data Sheet (231 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)