TOM70 Antibody (YA6808)
(Synonyms: FLJ9047 antibody; Mitochondrial import receptor subunit TOM70 antibody; Mitochondrial precursor proteins import receptor antibody; TOM70 antibody; TOM70_HUMAN antibody; Tomm70a antibody; Translocase of outer membrane 70 kDa subunit antibody; Translocase of outer membrane TOM70 antibody; Translocase of outer mitochondrial membrane 70 homolog A antibody; )
Based on 1 Customer Validation
TOM70 Antibody (YA6808) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TOM70.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, FC, ICC/IF, IP
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Reactivity :
Human, Mouse, Rat, Monkey
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|
| Dilution Ratio | 1:20000 | 1:200 | 1:100 | 1:1000 | 1-2μg/sample |
Product Details
TOM70 Antibody (YA6808) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TOM70.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat, Monkey
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Observed Molecular WeightObserved band size: 67 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 67 kDa
Recombinant protein within human TOM70 aa 86-608 / 608.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TOM70 acts as a receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner. Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection. Upon Sendai virus infection, recruits HSP90AA1:IRF3:BAX in mitochondrion and the complex induces apoptosis[1][2][3][4][5].
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Subcellular Localization
Mitochondrion outer membrane
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Isoforms & Post-Translational Modification
O94826: 608 amino acids, molecular weight 67455 Da.
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Subunit
Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70) (PubMed:18331822)
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SwissProt ID
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Synonyms
FLJ9047 antibody; Mitochondrial import receptor subunit TOM70 antibody; Mitochondrial precursor proteins import receptor antibody; TOM70 antibody; TOM70_HUMAN antibody; Tomm70a antibody; Translocase of outer membrane 70 kDa subunit antibody; Translocase of outer membrane TOM70 antibody; Translocase of outer mitochondrial membrane 70 homolog A antibody;
Documentation
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Data Sheet (231 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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User Guide for Antibodies (1077 KB)
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