TP53I3 (PIG3) Antibody (YA7898)(PBS only)

Cat. No.: HY-P88214A: Data Sheet User Guide for Antibodies
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TP53I3 (PIG3) Antibody (YA7898) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TP53I3 (PIG3).

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TP53I3 (PIG3) Antibody (YA7898) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TP53I3 (PIG3).

Host

Mouse

Molecular Weight

Predicted band size: 35.4 kDa

Species Reactivity

Human

SwissProt ID

Q53FA7

Immunogen

Full length human recombinant protein of human TP53I3 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Catalyzes the NADPH-dependent reduction of quinones (PubMed:19349281). Exhibits a low enzymatic activity with beta-naphthoquinones, with a strong preference for the ortho-quinone isomer (1,2-beta-naphthoquinone) over the para isomer (1,4-beta-naphthoquinone). Also displays a low reductase activity for non-quinone compounds such as diamine and 2,6-dichloroindophenol (in vitro) (PubMed:19349281). Involved in the generation of reactive oxygen species (ROS) (PubMed:19349281)

Expression：Induction: Isoform 1 and isoform 2 are both activated by p53/TP53, doxorubicin, etoposide and ionizing radiation. Isoform 2 is highly activated by UV radiation

Isoforms & Post-Translational Modification：Q53FA7 has two isomers: Q53FA7-1: 35536 Da (predicted); Q53FA7-2: 25402 Da (predicted).

Subunit：Homodimer

Synonyms

PIG3

Documentation

User Guide for Antibodies (1077 KB)