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Transmembrane Protein 30B Antibody (YA2220)(PBS only)

(Synonyms: CDC50B)

Transmembrane Protein 30B Antibody (YA2220) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transmembrane Protein 30B.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • Transmembrane Protein 30B Antibody (YA2220)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

Transmembrane Protein 30B Antibody (YA2220) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transmembrane Protein 30B.

  • Host Rabbit
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 39 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 39 kDa
Immunogen

Recombinant protein of human TMEM30B

Purification

Affinity Purified

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Transmembrane Protein 30B is an Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane

  • Subcellular Localization

    Cell membrane; Multi-pass membrane protein

  • Subunit

    Component of a P4-ATPase flippase complex which consists of a catalytic alpha subunit and an accessory beta subunit (Probable). Interacts with alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4

  • SwissProt ID

    Q3MIR4

  • Gene ID
    161291 [NCBI]
  • Synonyms

    CDC50B

  • Research Field

    Cell Biology

Transmembrane Protein 30B Antibody (YA2220)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • Transmembrane Protein 30B Antibody (YA2220)(PBS only) Product Image
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  • Transmembrane Protein 30B Antibody (YA2220)(PBS only) Product Image