AS-601811
AS-601811(compound 47) is a 5alpha-reductase 1 inhibitor with the IC50 of 20 nM and can be used for study of alopecia and hirsutism.
For research use only. We do not sell to patients.
- CAS No.: 194979-95-8
- Formula: C15H17NO
- Molecular Weight:227.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
20 nM
Compound: 39
|
Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells
Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells
|
[PMID: 11020287] |
Chemical Information
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CAS No. 194979-95-8
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Molecular Weight 227.30
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Formula C15H17NO
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SMILES
O=C1CCN2C3=CC=C(C)C=C3CCC2=C1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)