AZD-2327
AZD-2327 is a potent and selective δ-opioid receptor agonist. AZD-2327 binds to the human opioid receptor (Ki of 0.49 and 0.75 nM and EC50 of 24 and 9.2 nM at the C27 and F27 isoforms, respectively). AZD-2327 shows selectivity of >1000-fold over the human μ- and κ-opioid receptor subtypes as well as >130 other receptors and channels. AZD-2327 exhibits antidepressant and anxiolytic activities and can be used for the research of neurological disease.
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- CAS. Nr.: 875647-81-7
- Formel: C29H35FN4O
- Molecular Weight:474.61
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Alle Opioid Receptor Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
δ Opioid Receptor/DOR |
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 875647-81-7
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Molecular Weight 474.61
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Formel C29H35FN4O
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SMILES
CCN(CC)C(C(C=C1)=CC=C1[C@H](C2=CC(N)=CC=C2)N3CCN(CC4=CC=C(F)C=C4)CC3)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AZD-2327 Related Classifications
HY-108043 Related Classifications
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