TSPAN3 - tetraspanin 3 Gene

Also Known as TM4-A; TM4SF8; TSPAN-3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10099

About TSPAN3

Cytogenetic location: 15q24.3 Genomic coordinates (GRCh38): 15:77,041,404-77,071,109 (from NCBI)

This gene has 10 transcripts (splice variants), 285 orthologues and 32 paralogues. Ubiquitous expression in fat (RPKM 113.6), colon (RPKM 109.2) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Multiple alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Dec 2009]

TSPAN3 Products (3)

mRNA Protein Name
NM_001168412.2 NP_001161884.1 tetraspanin-3 isoform 3
NM_005724.6 NP_005715.1 tetraspanin-3 isoform 1
NM_198902.3 NP_944492.1 tetraspanin-3 isoform 2

TSPAN3 Protein Structure

Tetraspannin

Tetraspannin: Tetraspanin family (9 - 237)

  • 0
  • 100
  • 200
  • 253 a.a.
Protein Preferred Names Protein Names

tetraspanin-3

  • tetraspan 3

Related Diseases

Diseases Alias
Stormorken Syndrome

  • Thrombocytopathy, Asplenia, And Miosis

  • Stormorken-Sjaastad-Langslet Syndrome

  • STRMK

  • York Platelet Syndrome

  • Yps

  • Thrombocytopathy, Asplenia And Miosis

  • Thrombocytopathy Asplenia Miosis

  • Thrombocytopathy-Asplenia-Miosis Syndrome

  • Miosis Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15166 TSPAN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18102 Tspan3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24576 Tspan3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TSPAN3 VGNC VGNC:47919
Bos taurus TSPAN3 VGNC VGNC:36436
Mus musculus TSPAN3 MGD MGI:1928098
Rattus norvegicus TSPAN3 RGD RGD:1359444
Macaca mulatta TSPAN3 VGNC VGNC:79085
Macaca fascicularis TSPAN3 NCBI NCBI:102130140
Susscrofa domestica TSPAN3 NCBI
Others TSPAN3 NCBI