Cast - calpastatin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25403

Summary

Enables calcium-dependent cysteine-type endopeptidase inhibitor activity and protease binding activity. Involved in several processes, including animal organ development; egg activation; and myoblast fusion. Located in several cellular components, including cytoplasm; nucleus; and postsynaptic density. Used to study brain ischemia. Human ortholog(s) of this gene implicated in Parkinson's disease; autoimmune disease (multiple); congenital myasthenic syndrome 1A; and vasculitis. Orthologous to human CAST (calpastatin). [provided by Alliance of Genome Resources, Apr 2022]

Cast Products (3)

mRNA Protein Name
NM_001033715.1 NP_001028887.1 calpastatin isoform b
NM_001033716.1 NP_001028888.1 calpastatin isoform c
NM_053295.2 NP_445747.2 calpastatin isoform a
Protein Preferred Names Protein Names

calpastatin

  • calpain inhibitor

Cast Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
Cast P27321 Capn2 Rattus norvegicus Q07009
SPR
17543955
Cross: Cross-species interaction Intra: Intraspecies interaction

Orthologs Information

Species Symbol Source ID
Homo sapiens Cast NCBI NCBI:831