SURF6 - surfeit 6 Gene

Also Known as RRP14

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6838

About SURF6

Cytogenetic location: 9q34.2 Genomic coordinates (GRCh38): 9:133,328,776-133,336,188 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele and 178 orthologues. Ubiquitous expression in colon (RPKM 12.0), ovary (RPKM 11.5) and 25 other tissues.

Summary

This gene encodes a conserved protein that is localized to the nucleolus. The encoded protein may function as a nucleolar-matrix protein with nucleic acid-binding properties. There is a pseudogene for this gene on chromosome Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

SURF6 Products (2)

mRNA Protein Name
NM_001278942.2 NP_001265871.1 surfeit locus protein 6 isoform 2
NM_006753.6 NP_006744.2 surfeit locus protein 6 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables molecular condensate scaffold activity IDA
IDA: Inferred from direct assay
30498217 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
22113938 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SURF6 Protein Structure

SURF6

SURF6: Surfeit locus protein 6 (139 - 351)

  • 0
  • 100
  • 200
  • 300
  • 361 a.a.
Protein Preferred Names Protein Names

surfeit locus protein 6

SURF6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
SURF6 O75683 FAM9B Homo sapiens Q8IZU0
Validated Y2H
32296183
Intra
SURF6 O75683 RPL22 Homo sapiens P35268
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS14045 SURF6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SURF6 RGD RGD:1307382
Felis catus SURF6 VGNC VGNC:102991
Mus musculus SURF6 MGD MGI:98447
Bos taurus SURF6 VGNC VGNC:35485
Others SURF6 NCBI