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Art. -Nr.: HY-123452

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SCH 30497

SCH 30497 is a potent and orally active analgesic agent. SCH 30497 exhibits analgesic activity in the rat yeast-induced paw pain model, the mouse acetic acid-induced writhing test, and the squirrel monkey electric shock titration test. SCH 30497 can be used in pain research.

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CAS. Nr.: 83674-78-6
Formel: C₂₁H₂₄N₄O
Molecular Weight:348.44

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

SCH 30497 Chemical Structure

CAS. Nr.: 83674-78-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vivo

SCH 30497 demonstrats dose-dependent analgesic effects in a rat model of yeast-induced paw pain; at peak efficacy, the ED₅₀ values (in mg/kg) for oral, subcutaneous, intramuscular, and intravenous administration were 4.7, 5.7, 6.4, and 1.4, respectively^[1].
SCH 30497 also exhibits analgesic activity in the mouse acetic acid-induced writhing test (ED₅₀ = 1.9 mg/kg, oral administration) and the squirrel monkey shock titration test (ED₅₀ = 14.5 mg/kg, oral administration)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 83674-78-6
Molecular Weight 348.44
Formel C₂₁H₂₄N₄O
SMILES

O=C1N(N=C2C=CC=CN21)CCCN3CC=C(CC3)C4=CC=CC=C4C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Chipkin RE, et al. Pharmacological effects of SCH 30497--a novel analgesic substance. Arch Int Pharmacodyn Ther. 1985 Nov;278(1):23-44. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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