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TDO-IN-2

TDO-IN-2 (Compound 5c) is an orally active TDO inhibitor (IC50: 1.25 μM). TDO-IN-2 has antitumor activity in the Hepa1-6 hepatocellular carcinoma allograft mouse model. TDO-IN-2 has synergistic effects with the PD-1/PD-L1 inhibitor BMS-202 (HY-19745) and can be used to study tumor immune tolerance.

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  • Formel: C20H15N3O3
  • Molecular Weight:345.35
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • TDO-IN-2 Chemical Structure
    TDO-IN-2 Chemical Structure
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  • TDO-IN-2 Chemical Structure
    TDO-IN-2 Chemical Structure
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  • TDO-IN-2