T-1032
T-1032 is a selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 value of 1.0 nM. T-1032 shows relaxant effect on isolated rabbit corpus cavernosum. T-1032 can be used for the research of erectile dysfunction.
For research use only. We do not sell to patients.
- CAS No.: 212500-03-3
- Formula: C32H31N3O11S
- Molecular Weight:665.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
PDE5 1.0 nM (IC50) |
In Vitro
T-1032 (Compound 63) shows relaxant effect on isolated rabbit corpus cavernosum with an EC30 of 7.9 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 212500-03-3
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Molecular Weight 665.67
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Formula C32H31N3O11S
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SMILES
OS(O)(=O)=O.NC1=CC=C(N2C(C(OC)=O)=C(C3=CC(OC)=C(C(OC)=C3)OC)C4=C(C=C(C=C4)OCC5=NC=CC=C5)C2=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
T-1032 Related Classifications
HY-W705784A Related Classifications
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